deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

Gene fusions created by somatic genomic rearrangements are known to play an important role in the onset and development of some cancers, such as lymphomas and sarcomas. RNA-Seq (whole transcriptome shotgun sequencing) is proving to be a useful tool for the discovery of novel gene fusions in cancer t...

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Detalles Bibliográficos
Autores principales: McPherson, Andrew, Hormozdiari, Fereydoun, Zayed, Abdalnasser, Giuliany, Ryan, Ha, Gavin, Sun, Mark G. F., Griffith, Malachi, Heravi Moussavi, Alireza, Senz, Janine, Melnyk, Nataliya, Pacheco, Marina, Marra, Marco A., Hirst, Martin, Nielsen, Torsten O., Sahinalp, S. Cenk, Huntsman, David, Shah, Sohrab P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098195/
https://www.ncbi.nlm.nih.gov/pubmed/21625565
http://dx.doi.org/10.1371/journal.pcbi.1001138

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