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Protective Efficacy of Serially Up-Ranked Subdominant CD8(+) T Cell Epitopes against Virus Challenges

Immunodominance in T cell responses to complex antigens like viruses is still incompletely understood. Some data indicate that the dominant responses to viruses are not necessarily the most protective, while other data imply that dominant responses are the most important. The issue is of considerabl...

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Detalles Bibliográficos
Autores principales:	Im, Eung-Jun, Hong, Jessie P., Roshorm, Yaowaluck, Bridgeman, Anne, Létourneau, Sven, Liljeström, Peter, Potash, Mary Jane, Volsky, David J., McMichael, Andrew J., Hanke, Tomáš
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098219/ https://www.ncbi.nlm.nih.gov/pubmed/21625575 http://dx.doi.org/10.1371/journal.ppat.1002041

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