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Induction of HIV Neutralizing Antibodies against the MPER of the HIV Envelope Protein by HA/gp41 Chimeric Protein-Based DNA and VLP Vaccines

Several conserved neutralizing epitopes have been identified in the HIV Env protein and among these, the MPER of gp41 has received great attention and is widely recognized as a promising target. However, little success has been achieved in eliciting MPER-specific HIV neutralizing antibodies by a num...

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Detalles Bibliográficos
Autores principales: Ye, Ling, Wen, Zhiyuan, Dong, Ke, Wang, Xi, Bu, Zhigao, Zhang, Huizhong, Compans, Richard W., Yang, Chinglai
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098228/
https://www.ncbi.nlm.nih.gov/pubmed/21625584
http://dx.doi.org/10.1371/journal.pone.0014813