AAV Exploits Subcellular Stress Associated with Inflammation, Endoplasmic Reticulum Expansion, and Misfolded Proteins in Models of Cystic Fibrosis

Barriers to infection act at multiple levels to prevent viruses, bacteria, and parasites from commandeering host cells for their own purposes. An intriguing hypothesis is that if a cell experiences stress, such as that elicited by inflammation, endoplasmic reticulum (ER) expansion, or misfolded prot...

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Detalles Bibliográficos
Autores principales: Johnson, Jarrod S., Gentzsch, Martina, Zhang, Liqun, Ribeiro, Carla M. P., Kantor, Boris, Kafri, Tal, Pickles, Raymond J., Samulski, R. Jude
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098238/
https://www.ncbi.nlm.nih.gov/pubmed/21625534
http://dx.doi.org/10.1371/journal.ppat.1002053

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