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Co-Chaperone HSJ1a Dually Regulates the Proteasomal Degradation of Ataxin-3

Homo sapiens J domain protein (HSJ1) is a J-domain containing co-chaperone that is known to stimulate ATPase activity of HSP70 chaperone, while it also harbors two ubiquitin (Ub)-interacting motifs (UIMs) that may bind with ubiquitinated substrates and potentially function in protein degradation. We...

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Detalles Bibliográficos
Autores principales:	Gao, Xue-Chao, Zhou, Chen-Jie, Zhou, Zi-Ren, Zhang, Yu-Hang, Zheng, Xue-Ming, Song, Ai-Xin, Hu, Hong-Yu
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098244/ https://www.ncbi.nlm.nih.gov/pubmed/21625540 http://dx.doi.org/10.1371/journal.pone.0019763

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