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Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors
Pituitary adenylate cyclase activating polypeptide (PACAP) is a member of the PACAP/glucagon family of peptide hormones, which controls many physiological functions in the immune, nervous, endocrine, and muscular systems. It activates adenylate cyclase by binding to its receptor, PAC1R, a member of...
Autores principales: | Kumar, Shiva, Pioszak, Augen, Zhang, Chenghai, Swaminathan, Kunchithapadam, Xu, H. Eric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098264/ https://www.ncbi.nlm.nih.gov/pubmed/21625560 http://dx.doi.org/10.1371/journal.pone.0019682 |
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