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Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-β1

The signal transducer and activator of transcription-3 (STAT3) induces transcription of genes that control differentiation, inflammation, proliferation, and tumor cell invasion. Cytokines such as interleukin-6 and interferon stimulate the specific tyrosine phosphorylation of STAT3, which confers its...

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Detalles Bibliográficos
Autores principales: Cimica, Velasco, Chen, Hui-Chen, Iyer, Janaki K., Reich, Nancy C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098288/
https://www.ncbi.nlm.nih.gov/pubmed/21625522
http://dx.doi.org/10.1371/journal.pone.0020188