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Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-β1
The signal transducer and activator of transcription-3 (STAT3) induces transcription of genes that control differentiation, inflammation, proliferation, and tumor cell invasion. Cytokines such as interleukin-6 and interferon stimulate the specific tyrosine phosphorylation of STAT3, which confers its...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098288/ https://www.ncbi.nlm.nih.gov/pubmed/21625522 http://dx.doi.org/10.1371/journal.pone.0020188 |