Cargando…
Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1
Apoptosis provoked by glucose shortage in dividing T cells is mediated via the BH3-only protein Noxa and inhibition of its binding partner Mcl-1. It is unknown how signals from cellular metabolism can affect the balance between Mcl-1 and Noxa and to what extent other Bcl-2 members are involved in th...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098366/ https://www.ncbi.nlm.nih.gov/pubmed/21516346 http://dx.doi.org/10.1007/s10495-011-0599-8 |