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The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes
BACKGROUND & AIMS: The pro-inflammatory functions of NF-κB must be tightly regulated to prevent inappropriate tissue damage and remodelling caused by activated inflammatory and wound-healing cells. The p50 subunit of NF-κB is emerging as an important repressor of immune and inflammatory response...
Autores principales: | Elsharkawy, Ahmed M., Oakley, Fiona, Lin, Feng, Packham, Graham, Mann, Derek A., Mann, Jelena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098379/ https://www.ncbi.nlm.nih.gov/pubmed/20579762 http://dx.doi.org/10.1016/j.jhep.2010.03.025 |
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