Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection

Without therapy, most persons infected with the human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals (“elite controllers”) maintain very low levels of HIV RNA without therapy, thereby making disease progression and transmission unlikely. Certain HLA Class I alleles are ma...

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Detalles Bibliográficos
Autores principales: Košmrlj, Andrej, Read, Elizabeth L., Qi, Ying, Allen, Todd M., Altfeld, Marcus, Deeks, Steven G., Pereyra, Florencia, Carrington, Mary, Walker, Bruce D., Chakraborty, Arup K.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098720/
https://www.ncbi.nlm.nih.gov/pubmed/20445539
http://dx.doi.org/10.1038/nature08997

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