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Sequential interim analyses of survival data in DNA microarray experiments

BACKGROUND: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Frequently, microarray studies are performed to identify genes of which the expression levels in pretherapeutic tissue sample...

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Detalles Bibliográficos
Autores principales: Leha, Andreas, Beißbarth, Tim, Jung, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098786/
https://www.ncbi.nlm.nih.gov/pubmed/21527044
http://dx.doi.org/10.1186/1471-2105-12-127