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Sequential interim analyses of survival data in DNA microarray experiments
BACKGROUND: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Frequently, microarray studies are performed to identify genes of which the expression levels in pretherapeutic tissue sample...
Autores principales: | Leha, Andreas, Beißbarth, Tim, Jung, Klaus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098786/ https://www.ncbi.nlm.nih.gov/pubmed/21527044 http://dx.doi.org/10.1186/1471-2105-12-127 |
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