Cargando…
TRAIL-R4 Promotes Tumor Growth and Resistance to Apoptosis in Cervical Carcinoma HeLa Cells through AKT
BACKGROUND: TRAIL/Apo2L is a pro-apoptotic ligand of the TNF family that engages the apoptotic machinery through two pro-apoptotic receptors, TRAIL-R1 and TRAIL-R2. This cell death program is tightly controlled by two antagonistic receptors, TRAIL-R3 and TRAIL-R4, both devoid of a functional death d...
Autores principales: | Lalaoui, Najoua, Morlé, Aymeric, Mérino, Delphine, Jacquemin, Guillaume, Iessi, Elisabetta, Morizot, Alexandre, Shirley, Sarah, Robert, Bruno, Solary, Eric, Garrido, Carmen, Micheau, Olivier |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098831/ https://www.ncbi.nlm.nih.gov/pubmed/21625476 http://dx.doi.org/10.1371/journal.pone.0019679 |
Ejemplares similares
-
Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells
por: Iessi, Elisabetta, et al.
Publicado: (2015) -
TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
por: Dufour, Florent, et al.
Publicado: (2016) -
Regulating TRAIL Receptor-Induced Cell Death at the Membrane: A Deadly Discussion
por: Shirley, Sarah, et al.
Publicado: (2011) -
N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death
por: Dufour, Florent, et al.
Publicado: (2017) -
Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion
por: Morlé, A, et al.
Publicado: (2015)