Cargando…

High Throughput Determination of TGFβ1/SMAD3 Targets in A549 Lung Epithelial Cells

BACKGROUND: Transforming growth factor beta 1 (TGFβ1) plays a major role in many lung diseases including lung cancer, pulmonary hypertension, and pulmonary fibrosis. TGFβ1 activates a signal transduction cascade that results in the transcriptional regulation of genes in the nucleus, primarily throug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yingze, Handley, Daniel, Kaplan, Tommy, Yu, Haiying, Bais, Abha S., Richards, Thomas, Pandit, Kusum V., Zeng, Qilu, Benos, Panayiotis V., Friedman, Nir, Eickelberg, Oliver, Kaminski, Naftali
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098871/ https://www.ncbi.nlm.nih.gov/pubmed/21625455 http://dx.doi.org/10.1371/journal.pone.0020319

Ejemplares similares

Finding subtypes of transcription factor motif pairs with distinct regulatory roles
por: Bais, Abha Singh, et al.
Publicado: (2011)

Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density
por: Coronnello, Claudia, et al.
Publicado: (2012)

Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data
por: Corcoran, David L., et al.
Publicado: (2009)

Dexamethasone induced apoptosis of A549 cells via the TGF-β1/Smad2 pathway
por: Feng, Xiao-Ling, et al.
Publicado: (2018)

Cartilage Oligomeric Matrix Protein in Idiopathic Pulmonary Fibrosis
por: Vuga, Louis J., et al.
Publicado: (2013)

Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway
por: Chen, Kui-Jun, et al.
Publicado: (2016)

Novel Alternatively Spliced Variants of Smad4 Expressed in TGF-β-Induced EMT Regulating Proliferation and Migration of A549 Cells
por: Wan, Rongxue, et al.
Publicado: (2020)

Repression of Smad4 by miR-205 moderates TGF-β-induced epithelial-mesenchymal transition in A549 cell lines
por: Zeng, Yuanyuan, et al.
Publicado: (2021)

Expression of Regulatory Platelet MicroRNAs in Patients with Sickle Cell Disease
por: Jain, Shilpa, et al.
Publicado: (2013)

Global Methylation Patterns in Idiopathic Pulmonary Fibrosis
por: Rabinovich, Einat I., et al.
Publicado: (2012)

STAMP: a web tool for exploring DNA-binding motif similarities
por: Mahony, Shaun, et al.
Publicado: (2007)

ComiR: combinatorial microRNA target prediction tool
por: Coronnello, Claudia, et al.
Publicado: (2013)

SB431542 inhibited cigarette smoke extract induced invasiveness of A549 cells via the TGF-β1/Smad2/MMP3 pathway
por: Liao, Ke, et al.
Publicado: (2018)

The Epithelial-to-Mesenchymal Transition-Like Process Induced by TGF-β1 Enhances Rubella Virus Binding and Infection in A549 Cells via the Smad Pathway
por: Pham, Ngan Thi Kim, et al.
Publicado: (2021)

Ab Initio Prediction of Transcription Factor Targets Using Structural Knowledge
por: Kaplan, Tommy, et al.
Publicado: (2005)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

mirConnX: condition-specific mRNA-microRNA network integrator
por: Huang, Grace T., et al.
Publicado: (2011)

HHMMiR: efficient de novo prediction of microRNAs using hierarchical hidden Markov models
por: Kadri, Sabah, et al.
Publicado: (2009)

Smad2-Dependent Downregulation of miR-30 Is Required for TGF-β-Induced Apoptosis in Podocytes
por: Shi, Shaolin, et al.
Publicado: (2013)

TGF-Beta Induced Erk Phosphorylation of Smad Linker Region Regulates Smad Signaling
por: Hough, Chris, et al.
Publicado: (2012)

SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4
por: Bertrand-Chapel, Adrien, et al.
Publicado: (2022)

DNA Familial Binding Profiles Made Easy: Comparison of Various Motif Alignment and Clustering Strategies
por: Mahony, Shaun, et al.
Publicado: (2007)

FOOTER: a web tool for finding mammalian DNA regulatory regions using phylogenetic footprinting
por: Corcoran, David L., et al.
Publicado: (2005)

RNA Deep Sequencing Reveals Differential MicroRNA Expression during Development of Sea Urchin and Sea Star
por: Kadri, Sabah, et al.
Publicado: (2011)

To bind or not to bind - FoxA1 determines estrogen receptor action in breast cancer progression
por: Watters, Rebecca J, et al.
Publicado: (2012)

Causal network perturbations for instance-specific analysis of single cell and disease samples
por: Buschur, Kristina L, et al.
Publicado: (2020)

Protecting the lungs but hurting the kidneys: causal inference study for the risk of ventilation-induced kidney injury in ARDS
por: Yang, Haopu, et al.
Publicado: (2020)

A Novel Bayesian DNA Motif Comparison Method for Clustering and Retrieval
por: Habib, Naomi, et al.
Publicado: (2008)

Nucleosome positioning from tiling microarray data
por: Yassour, Moran, et al.
Publicado: (2008)

Correction: A Novel Bayesian DNA Motif Comparison Method for Clustering and Retrieval
por: Habib, Naomi, et al.
Publicado: (2011)

Smad4-mediated TGF-β signaling in tumorigenesis
por: Yang, Guan, et al.
Publicado: (2010)

The regulation of TGF-β/SMAD signaling by protein deubiquitination
por: Zhang, Juan, et al.
Publicado: (2014)

The role of TGF-β/SMAD4 signaling in cancer
por: Zhao, Ming, et al.
Publicado: (2018)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Effect of progesterone on Smad signaling and TGF-β/Smad-regulated genes in lung epithelial cells
por: Kunzmann, Steffen, et al.
Publicado: (2018)

Electrostatic hot spot on DNA-binding domains mediates phosphate desolvation and the pre-organization of specificity determinant side chains
por: Temiz, Alpay N., et al.
Publicado: (2010)

An improvement of ComiR algorithm for microRNA target prediction by exploiting coding region sequences of mRNAs
por: Bertolazzi, Giorgio, et al.
Publicado: (2020)

The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas
por: Zhenye, Li, et al.
Publicado: (2014)

Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway
por: Kang, Heeseog, et al.
Publicado: (2020)

TGF-β and TGF-β/Smad Signaling in the Interactions between Echinococcus multilocularis and Its Hosts
por: Wang, Junhua, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_up2jfi4ojl5fbn7j2kqlvdqfa5