Cargando…
Variation in NOD2 Augments Th2- and Th17 Responses to Myelin Basic Protein in Multiple Sclerosis
Variations in the gene for the nucleotide-binding oligomerisation domain (NOD) 2 have been associated with Crohn's disease but not multiple sclerosis (MS). Here we investigate the effect of three polymorphisms in the NOD2 gene (rs5743277, rs2066842 and rs5743291) on cytokine production and CD4+...
Autores principales: | Hedegaard, Chris Juul, Enevold, Christian, Sellebjerg, Finn, Bendtzen, Klaus, Nielsen, Claus Henrik |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098873/ https://www.ncbi.nlm.nih.gov/pubmed/21625457 http://dx.doi.org/10.1371/journal.pone.0020253 |
Ejemplares similares
-
Endogenous Interferon-β-Inducible Gene Expression and Interferon-β-Treatment Are Associated with Reduced T Cell Responses to Myelin Basic Protein in Multiple Sclerosis
por: Börnsen, Lars, et al.
Publicado: (2015) -
Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis
por: Nielsen, Claus H., et al.
Publicado: (2016) -
Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression
por: Christensen, Jeppe Romme, et al.
Publicado: (2013) -
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis
por: Napier, Ruth J., et al.
Publicado: (2020) -
Correction: Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression
por: Romme Christensen, Jeppe, et al.
Publicado: (2013)