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Evaluating Nuclei Concentration in Amyloid Fibrillation Reactions Using Back-Calculation Approach
BACKGROUND: In spite of our extensive knowledge of the more than 20 proteins associated with different amyloid diseases, we do not know how amyloid toxicity occurs or how to block its action. Recent contradictory reports suggest that the fibrils and/or the oligomer precursors cause toxicity. An esti...
Autores principales: | Sorci, Mirco, Silkworth, Whitney, Gehan, Timothy, Belfort, Georges |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098880/ https://www.ncbi.nlm.nih.gov/pubmed/21625464 http://dx.doi.org/10.1371/journal.pone.0020072 |
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