Genetics of Mechanosensation in the Heart

Mechanosensation (the ultimate conversion of a mechanical stimulus into a biochemical signal) as well as mechanotransduction (transmission of mechanically induced signals) belong to the most fundamental processes in biology. These effects, because of their dynamic nature, are particularly important...

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Autores principales: Buyandelger, Byambajav, Ng, Keat-Eng, Miocic, Snjezana, Gunkel, Sylvia, Piotrowska, Izabela, Ku, Ching-Hsin, Knöll, Ralph
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098994/
https://www.ncbi.nlm.nih.gov/pubmed/21360311
http://dx.doi.org/10.1007/s12265-011-9262-6
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author Buyandelger, Byambajav
Ng, Keat-Eng
Miocic, Snjezana
Gunkel, Sylvia
Piotrowska, Izabela
Ku, Ching-Hsin
Knöll, Ralph
author_facet Buyandelger, Byambajav
Ng, Keat-Eng
Miocic, Snjezana
Gunkel, Sylvia
Piotrowska, Izabela
Ku, Ching-Hsin
Knöll, Ralph
author_sort Buyandelger, Byambajav
collection PubMed
description Mechanosensation (the ultimate conversion of a mechanical stimulus into a biochemical signal) as well as mechanotransduction (transmission of mechanically induced signals) belong to the most fundamental processes in biology. These effects, because of their dynamic nature, are particularly important for the cardiovascular system. Therefore, it is not surprising that defects in cardiac mechanosensation, are associated with various types of cardiomyopathy and heart failure. However, our current knowledge regarding the genetic basis of impaired mechanosensation in the cardiovascular system is beginning to shed light on this subject and is at the centre of this brief review.
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spelling pubmed-30989942011-07-14 Genetics of Mechanosensation in the Heart Buyandelger, Byambajav Ng, Keat-Eng Miocic, Snjezana Gunkel, Sylvia Piotrowska, Izabela Ku, Ching-Hsin Knöll, Ralph J Cardiovasc Transl Res Article Mechanosensation (the ultimate conversion of a mechanical stimulus into a biochemical signal) as well as mechanotransduction (transmission of mechanically induced signals) belong to the most fundamental processes in biology. These effects, because of their dynamic nature, are particularly important for the cardiovascular system. Therefore, it is not surprising that defects in cardiac mechanosensation, are associated with various types of cardiomyopathy and heart failure. However, our current knowledge regarding the genetic basis of impaired mechanosensation in the cardiovascular system is beginning to shed light on this subject and is at the centre of this brief review. Springer US 2011-03-01 2011 /pmc/articles/PMC3098994/ /pubmed/21360311 http://dx.doi.org/10.1007/s12265-011-9262-6 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Buyandelger, Byambajav
Ng, Keat-Eng
Miocic, Snjezana
Gunkel, Sylvia
Piotrowska, Izabela
Ku, Ching-Hsin
Knöll, Ralph
Genetics of Mechanosensation in the Heart
title Genetics of Mechanosensation in the Heart
title_full Genetics of Mechanosensation in the Heart
title_fullStr Genetics of Mechanosensation in the Heart
title_full_unstemmed Genetics of Mechanosensation in the Heart
title_short Genetics of Mechanosensation in the Heart
title_sort genetics of mechanosensation in the heart
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098994/
https://www.ncbi.nlm.nih.gov/pubmed/21360311
http://dx.doi.org/10.1007/s12265-011-9262-6
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