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A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice
The hush puppy mouse mutant has been shown previously to have skull and outer, middle, and inner ear defects, and an increase in hearing threshold. The fibroblast growth factor receptor 1 (Fgfr1) gene is located in the region of chromosome 8 containing the mutation. Sequencing of the gene in hush pu...
Autores principales: | Calvert, Jennifer A., Dedos, Skarlatos G., Hawker, Kelvin, Fleming, Michelle, Lewis, Morag A., Steel, Karen P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099004/ https://www.ncbi.nlm.nih.gov/pubmed/21479780 http://dx.doi.org/10.1007/s00335-011-9324-8 |
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