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Diffuse alveolar hemorrhage in Wegener’s granulomatosis

Diffuse alveolar hemorrhage is a life-threatening though rare manifestation of Wegener’s granulomatosis (WG). An active diagnostic workup, intensive observation, and aggressive immunosuppressive treatment are cornerstones of the management. The treatment modalities available for such complications a...

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Detalles Bibliográficos
Autores principales: Mahajan, Vineet, Whig, Jagdeep, Kashyap, Anil, Gupta, Sushil
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099512/
https://www.ncbi.nlm.nih.gov/pubmed/21654987
http://dx.doi.org/10.4103/0970-2113.76302
Descripción
Sumario:Diffuse alveolar hemorrhage is a life-threatening though rare manifestation of Wegener’s granulomatosis (WG). An active diagnostic workup, intensive observation, and aggressive immunosuppressive treatment are cornerstones of the management. The treatment modalities available for such complications are pulse cyclophosphamide therapy with steroids. We report here a case of WG with diffuse alveolar hemorrhage as the first manifestation of the disease in life that responded to steroids and cyclophosphamide.