2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone

In the title compound, C(27)H(30)O(6), also known as sofalcone, an anti-ulcer agent used for the protection of gastric mucosa­, the two benzene rings form a dihedral angle of 6.78 (11)°. Inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers, which are further linked by...

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Detalles Bibliográficos
Autores principales: Liang, Yan-Shu, Mu, Shuai, Wang, Jing-Yang, Liu, Deng-Ke
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099935/
https://www.ncbi.nlm.nih.gov/pubmed/21754114
http://dx.doi.org/10.1107/S1600536811008300
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author Liang, Yan-Shu
Mu, Shuai
Wang, Jing-Yang
Liu, Deng-Ke
author_facet Liang, Yan-Shu
Mu, Shuai
Wang, Jing-Yang
Liu, Deng-Ke
author_sort Liang, Yan-Shu
collection PubMed
description In the title compound, C(27)H(30)O(6), also known as sofalcone, an anti-ulcer agent used for the protection of gastric mucosa­, the two benzene rings form a dihedral angle of 6.78 (11)°. Inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers, which are further linked by weak C—H⋯O inter­actions into ribbons propagated in [2[Image: see text]0]. Finally, π–π inter­actions between the benzene rings [centroid–centroid distance = 3.583 (13) Å] stabilize the crystal packing.
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spelling pubmed-30999352011-07-13 2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone Liang, Yan-Shu Mu, Shuai Wang, Jing-Yang Liu, Deng-Ke Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(27)H(30)O(6), also known as sofalcone, an anti-ulcer agent used for the protection of gastric mucosa­, the two benzene rings form a dihedral angle of 6.78 (11)°. Inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers, which are further linked by weak C—H⋯O inter­actions into ribbons propagated in [2[Image: see text]0]. Finally, π–π inter­actions between the benzene rings [centroid–centroid distance = 3.583 (13) Å] stabilize the crystal packing. International Union of Crystallography 2011-03-09 /pmc/articles/PMC3099935/ /pubmed/21754114 http://dx.doi.org/10.1107/S1600536811008300 Text en © Liang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Liang, Yan-Shu
Mu, Shuai
Wang, Jing-Yang
Liu, Deng-Ke
2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
title 2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
title_full 2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
title_fullStr 2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
title_full_unstemmed 2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
title_short 2′-Carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
title_sort 2′-carb­oxy­meth­oxy-4,4′-bis­(3-methyl­but-2-en­yloxy)chalcone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099935/
https://www.ncbi.nlm.nih.gov/pubmed/21754114
http://dx.doi.org/10.1107/S1600536811008300
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AT mushuai 2carboxymethoxy44bis3methylbut2enyloxychalcone
AT wangjingyang 2carboxymethoxy44bis3methylbut2enyloxychalcone
AT liudengke 2carboxymethoxy44bis3methylbut2enyloxychalcone

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