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4,5-Bis(4-fluorophenyl)-5-hydroxy-3-(2-methylpropanoyl)-1-phenylpyrrolidin-2-one
The title compound, C(26)H(23)F(2)NO(3), was synthesized by the reaction of 2-(4-fluorobenzylidene)-4-methyl-3-oxo-N-phenylpentanamide and 4-fluorobenzaldehyde. The dihedral angles between the mean plane through the pyrrolidine ring (nearly planar; maximum deviation of 0.145 Å for the C atom be...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099992/ https://www.ncbi.nlm.nih.gov/pubmed/21754151 http://dx.doi.org/10.1107/S1600536811008786 |
Sumario: | The title compound, C(26)H(23)F(2)NO(3), was synthesized by the reaction of 2-(4-fluorobenzylidene)-4-methyl-3-oxo-N-phenylpentanamide and 4-fluorobenzaldehyde. The dihedral angles between the mean plane through the pyrrolidine ring (nearly planar; maximum deviation of 0.145 Å for the C atom bearing the hydroxy group) with the phenyl and benzene rings are 37.22 (7), 51.88 (7) and 87.64 (9)°, respectively. The pyyolidine ring is near coplaner, with max offset of 0.145 A for C19 atom.\uff09 In the crystal, molecules are linked by pairs of O—H⋯O hydrogen bonds into inversion dimers, which are further assembled into chains parallel to the b axis by weak C—H⋯O hydrogen bonds. |
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