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4,5-Bis(4-fluoro­phen­yl)-5-hy­droxy-3-(2-methyl­propano­yl)-1-phenyl­pyrrolidin-2-one

The title compound, C(26)H(23)F(2)NO(3), was synthesized by the reaction of 2-(4-fluoro­benzyl­idene)-4-methyl-3-oxo-N-phenyl­penta­namide and 4-fluoro­benzaldehyde. The dihedral angles between the mean plane through the pyrrolidine ring (nearly planar; maximum deviation of 0.145 Å for the C atom be...

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Detalles Bibliográficos
Autores principales: Huang, Jian-Ying, Zhou, Fengyan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099992/
https://www.ncbi.nlm.nih.gov/pubmed/21754151
http://dx.doi.org/10.1107/S1600536811008786
Descripción
Sumario:The title compound, C(26)H(23)F(2)NO(3), was synthesized by the reaction of 2-(4-fluoro­benzyl­idene)-4-methyl-3-oxo-N-phenyl­penta­namide and 4-fluoro­benzaldehyde. The dihedral angles between the mean plane through the pyrrolidine ring (nearly planar; maximum deviation of 0.145 Å for the C atom bearing the hydroxy group) with the phenyl and benzene rings are 37.22 (7), 51.88 (7) and 87.64 (9)°, respectively. The pyyolidine ring is near coplaner, with max offset of 0.145 A for C19 atom.\uff09 In the crystal, mol­ecules are linked by pairs of O—H⋯O hydrogen bonds into inversion dimers, which are further assembled into chains parallel to the b axis by weak C—H⋯O hydrogen bonds.