2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid

The title compound, C(8)H(14)O(4), is an isolation product of the aerial parts of Senecio desfontanei. The acetic acid group is oriented at a dihedral angle of 48.03 (9)° with respect to the basal plane of the cyclo­hexane-1,4-diol chair. An intra­molecular O—H⋯O hydrogen bond generates an S(6) ring...

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Autores principales: Arfan, Mohammad, Hussain, Syed Hamid, Tahir, M. Nawaz, Rafique, Jamal, Shaheen, Farzana
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100032/
https://www.ncbi.nlm.nih.gov/pubmed/21754231
http://dx.doi.org/10.1107/S1600536811010397
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author Arfan, Mohammad
Hussain, Syed Hamid
Tahir, M. Nawaz
Rafique, Jamal
Shaheen, Farzana
author_facet Arfan, Mohammad
Hussain, Syed Hamid
Tahir, M. Nawaz
Rafique, Jamal
Shaheen, Farzana
author_sort Arfan, Mohammad
collection PubMed
description The title compound, C(8)H(14)O(4), is an isolation product of the aerial parts of Senecio desfontanei. The acetic acid group is oriented at a dihedral angle of 48.03 (9)° with respect to the basal plane of the cyclo­hexane-1,4-diol chair. An intra­molecular O—H⋯O hydrogen bond generates an S(6) ring with an envelope conformation. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, resulting in R (3) (3)(20) ring motifs and C(2) O—H⋯O—H⋯O—H⋯ chains. Overall, a three-dimensional polymeric network arises. A C—H⋯O contact is also present.
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spelling pubmed-31000322011-07-13 2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid Arfan, Mohammad Hussain, Syed Hamid Tahir, M. Nawaz Rafique, Jamal Shaheen, Farzana Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(8)H(14)O(4), is an isolation product of the aerial parts of Senecio desfontanei. The acetic acid group is oriented at a dihedral angle of 48.03 (9)° with respect to the basal plane of the cyclo­hexane-1,4-diol chair. An intra­molecular O—H⋯O hydrogen bond generates an S(6) ring with an envelope conformation. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, resulting in R (3) (3)(20) ring motifs and C(2) O—H⋯O—H⋯O—H⋯ chains. Overall, a three-dimensional polymeric network arises. A C—H⋯O contact is also present. International Union of Crystallography 2011-03-26 /pmc/articles/PMC3100032/ /pubmed/21754231 http://dx.doi.org/10.1107/S1600536811010397 Text en © Arfan et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Arfan, Mohammad
Hussain, Syed Hamid
Tahir, M. Nawaz
Rafique, Jamal
Shaheen, Farzana
2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid
title 2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid
title_full 2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid
title_fullStr 2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid
title_full_unstemmed 2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid
title_short 2-[(1R*,4R*)-1,4-Dihy­droxy­cyclo­hex­yl]acetic acid
title_sort 2-[(1r*,4r*)-1,4-dihy­droxy­cyclo­hex­yl]acetic acid
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100032/
https://www.ncbi.nlm.nih.gov/pubmed/21754231
http://dx.doi.org/10.1107/S1600536811010397
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AT tahirmnawaz 21r4r14dihydroxycyclohexylaceticacid
AT rafiquejamal 21r4r14dihydroxycyclohexylaceticacid
AT shaheenfarzana 21r4r14dihydroxycyclohexylaceticacid

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