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Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells

Brain endothelial cells play an essential role as structural and functional components of the blood–brain barrier (BBB). Increased BBB breakdown and brain injury are associated with neuroinflammation and are thought to trigger mechanisms involving matrix metalloproteinase upregulation. Emerging evid...

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Detalles Bibliográficos
Autores principales:	Tahanian, Elizabeth, Sanchez, Luis Arguello, Shiao, Tze Chieh, Roy, René, Annabi, Borhane
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100225/ https://www.ncbi.nlm.nih.gov/pubmed/21625419 http://dx.doi.org/10.2147/DDDT.S19931

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