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Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells

BACKGROUND: NASP (Nuclear Autoantigenic Sperm Protein) is a histone chaperone that is present in all dividing cells. NASP has two splice variants: tNASP and sNASP. Only cancer, germ, transformed, and embryonic cells have a high level of expression of the tNASP splice variant. We examined the consequ...

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Detalles Bibliográficos
Autores principales:	Alekseev, Oleg M, Richardson, Richard T, Tsuruta, James K, O'Rand, Michael G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100250/ https://www.ncbi.nlm.nih.gov/pubmed/21496299 http://dx.doi.org/10.1186/1477-7827-9-50

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