Cargando…

Non-Integrative Lentivirus Drives High-Frequency cre-Mediated Cassette Exchange in Human Cells

Recombinase mediated cassette exchange (RMCE) is a two-step process leading to genetic modification in a specific genomic target sequence. The process involves insertion of a docking genetic cassette in the genome followed by DNA transfer of a second cassette flanked by compatible recombination sign...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Raul, García, Aida, Payá, Monica, Ramirez, Juan C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100306/
https://www.ncbi.nlm.nih.gov/pubmed/21625434
http://dx.doi.org/10.1371/journal.pone.0019794