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Non-Integrative Lentivirus Drives High-Frequency cre-Mediated Cassette Exchange in Human Cells
Recombinase mediated cassette exchange (RMCE) is a two-step process leading to genetic modification in a specific genomic target sequence. The process involves insertion of a docking genetic cassette in the genome followed by DNA transfer of a second cassette flanked by compatible recombination sign...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100306/ https://www.ncbi.nlm.nih.gov/pubmed/21625434 http://dx.doi.org/10.1371/journal.pone.0019794 |