Cargando…

Cleavage of Kininogen and Subsequent Bradykinin Release by the Complement Component: Mannose-Binding Lectin-Associated Serine Protease (MASP)-1

Bradykinin (BK), generated from high-molecular-weight kininogen (HK) is the major mediator of swelling attacks in hereditary angioedema (HAE), a disease associated with C1-inhibitor deficiency. Plasma kallikrein, activated by factor XIIa, is responsible for most of HK cleavage. However other proteas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dobó, József, Major, Balázs, Kékesi, Katalin A., Szabó, István, Megyeri, Márton, Hajela, Krishnan, Juhász, Gábor, Závodszky, Péter, Gál, Péter
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100311/ https://www.ncbi.nlm.nih.gov/pubmed/21625439 http://dx.doi.org/10.1371/journal.pone.0020036

Ejemplares similares

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins
por: De Marco Verissimo, Carolina, et al.
Publicado: (2022)

Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism
por: Oroszlán, Gábor, et al.
Publicado: (2017)

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked
por: Dobó, József, et al.
Publicado: (2016)

Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway
por: Wallis, Russell
Publicado: (2007)

Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides
por: Dürvanger, Zsolt, et al.
Publicado: (2022)

MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1
por: Jenny, Lorenz, et al.
Publicado: (2015)

Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours
por: Swierzko, Anna St., et al.
Publicado: (2014)

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2017)

Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2017)

Bradykinin Release Avoids High Molecular Weight Kininogen Endocytosis
por: Damasceno, Igor Z., et al.
Publicado: (2015)

MASP-1 Induces a Unique Cytokine Pattern in Endothelial Cells: A Novel Link between Complement System and Neutrophil Granulocytes
por: Jani, Péter K., et al.
Publicado: (2014)

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
por: Orsini, Franca, et al.
Publicado: (2016)

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model
por: Golomingi, Murielle, et al.
Publicado: (2022)

C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo
por: Ruseva, M M, et al.
Publicado: (2014)

Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
por: Nagy, Zoltán Attila, et al.
Publicado: (2022)

Prevalence of the polymorphic H-f icolin (FCN3) genes and mannose-binding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions
por: Smolnikova, M.V., et al.
Publicado: (2021)

MASP-1 Increases Endothelial Permeability
por: Debreczeni, Márta L., et al.
Publicado: (2019)

Effects of MASP-1 of the Complement System on Activation of Coagulation Factors and Plasma Clot Formation
por: Hess, Katharina, et al.
Publicado: (2012)

Cooperation of Complement MASP-1 with Other Proinflammatory Factors to Enhance the Activation of Endothelial Cells
por: Németh, Zsuzsanna, et al.
Publicado: (2023)

MBL-associated serine proteases (MASPs) and infectious diseases
por: Beltrame, Marcia H., et al.
Publicado: (2015)

The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
por: Kusakari, Kohei, et al.
Publicado: (2022)

Pentraxin 3, ficolin-2 and lectin pathway associated serine protease MASP-3 as early predictors of myocardial infarction - the HUNT2 study
por: Vengen, Inga Thorsen, et al.
Publicado: (2017)

MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model
por: Jenny, Lorenz, et al.
Publicado: (2018)

Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19
por: Götz, Maximilian Peter, et al.
Publicado: (2022)

Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors
por: Szakács, Dávid, et al.
Publicado: (2019)

Kininogen Cleavage Assay: Diagnostic Assistance for Kinin-Mediated Angioedema Conditions
por: Baroso, Rémi, et al.
Publicado: (2016)

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel
por: Zachar, Rikke, et al.
Publicado: (2022)

Transcriptome analysis of inflammation-related gene expression in endothelial cells activated by complement MASP-1
por: Schwaner, Endre, et al.
Publicado: (2017)

The blood fluke Schistosoma mansoni cleaves the coagulation protein high molecular weight kininogen (HK) but does not generate the vasodilator bradykinin
por: Wang, Qiang, et al.
Publicado: (2018)

Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D
por: Takahashi, Minoru, et al.
Publicado: (2010)

Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases
por: Dobó, József, et al.
Publicado: (2018)

Mouse Ficolin B Has an Ability to Form Complexes with Mannose-Binding Lectin-Associated Serine Proteases and Activate Complement through the Lectin Pathway
por: Endo, Yuichi, et al.
Publicado: (2012)

Should MASP-2 Deficiency Be Considered a Primary Immunodeficiency? Relevance of the Lectin Pathway
por: García-Laorden, M. Isabel, et al.
Publicado: (2019)

Polymorphisms in the MASP1 Gene Are Associated with Serum Levels of MASP-1, MASP-3, and MAp44
por: Gytz Ammitzbøll, Christian, et al.
Publicado: (2013)

The Serine Protease Domain of MASP-3: Enzymatic Properties and Crystal Structure in Complex with Ecotin
por: Gaboriaud, Christine, et al.
Publicado: (2013)

Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
por: Flude, Ben M., et al.
Publicado: (2021)

Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type-1 diabetes
por: Merchant, Michael L., et al.
Publicado: (2013)

Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria
por: Holmberg, Ville, et al.
Publicado: (2012)

Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn’s Disease Patients
por: Choteau, Laura, et al.
Publicado: (2016)

Role of mannose-binding lectin on pneumococcal infections
por: Solé Violán, J, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_e99kf7dbdfs8bb93h9q9pn3j13