Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes

The long-term objective of this project is to utilize the I-domain protein for the α-subunit of LFA-1 to target drugs to lymphocytes by binding to ICAM receptors on the cell surface. The short-term goal is to provide proof-of-concept that I-domain conjugated to small molecules can still bind to and...

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Detalles Bibliográficos
Autores principales: Manikwar, Prakash, Tejo, Bimo A., Shinogle, Heather, Moore, David S., Zimmerman, Tahl, Blanco, Francisco, Siahaan, Teruna J.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100608/
https://www.ncbi.nlm.nih.gov/pubmed/21611107

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