Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia

Nucleophosmin (NPM1) gene mutations resulting in cytoplasmic delocalization of Nucleophosmin (NPMc+) are the most common genetic alteration in acute myeloid leukemia (AML). Here, we attempted to prepare monoclonal antibodies (mAbs) against NPM1 mutation A (NPM-mA) and investigated the mAbs' cli...

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Detalles Bibliográficos
Autores principales: Tan, Shi, Zhang, Ling, Zhong, Xiao-Ming, Yang, Zai-Lin, Zhao, Liu-Yang, Gao, Yu-Jie, Shao, Hui-Yuan, Qin, Feng-Xian, Chen, Xian-Chun, Zhang, Hui-Juan, Chen, Hui, Wang, Li
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100738/
https://www.ncbi.nlm.nih.gov/pubmed/21611112

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