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Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer
Dysregulation of the cell cycle is the underlying mechanism of neoplasia. Healthy cells prevent propagation of DNA mutations to progeny by activation of cellular checkpoints, which allows time for DNA repair. On the other hand, activation of the DNA damage response is also the general principle of m...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Faculty of 1000 Ltd
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100786/ https://www.ncbi.nlm.nih.gov/pubmed/21655336 http://dx.doi.org/10.3410/B3-10 |