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Dysregulated Neuronal Activity Patterns Implicate Corticostriatal Circuit Dysfunction in Multiple Rodent Models of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that targets the corticostriatal system and results in progressive deterioration of cognitive, emotional, and motor skills. Although cortical and striatal neurons are widely studied in animal models of HD, there is li...

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Detalles Bibliográficos
Autores principales: Miller, Benjamin R., Walker, Adam G., Barton, Scott J., Rebec, George V.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100808/
https://www.ncbi.nlm.nih.gov/pubmed/21629717
http://dx.doi.org/10.3389/fnsys.2011.00026