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C-Jun NH(2)-Terminal Kinase Contributes to Dexmedetomidine-Induced Contraction in Isolated Rat Aortic Smooth Muscle

PURPOSE: Dexmedetomidine, a full agonist of α(2B)-adrenoceptors, is used for analgesia and sedation in the intensive care units. Dexmedetomidine produces an initial transient hypertension due to the activation of post-junctional α(2B)-adrenoceptors on vascular smooth muscle cells (SMCs). The aims of...

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Detalles Bibliográficos
Autores principales:	Ok, Seong-Ho, Jeong, Young Seok, Kim, Jae-Gak, Lee, Seung-Min, Sung, Hui-Jin, Kim, Hye Jung, Chang, Ki Churl, Kwon, Seong-Chun, Sohn, Ju-Tae
Formato:	Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101051/ https://www.ncbi.nlm.nih.gov/pubmed/21488184 http://dx.doi.org/10.3349/ymj.2011.52.3.420

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