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Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling

Spinal muscular atrophy (SMA), a devastating neurodegenerative disorder characterized by motor neuron loss and muscle atrophy, has been linked to mutations in the Survival Motor Neuron (SMN) gene. Based on an SMA model we developed in Drosophila, which displays features that are analogous to the hum...

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Detalles Bibliográficos
Autores principales:	Sen, Anindya, Yokokura, Takakazu, Kankel, Mark W., Dimlich, Douglas N., Manent, Jan, Sanyal, Subhabrata, Artavanis-Tsakonas, Spyros
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101100/ https://www.ncbi.nlm.nih.gov/pubmed/21300852 http://dx.doi.org/10.1083/jcb.201004016

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