Cargando…

Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging

Receptor dimerization is important for many signaling pathways. However, the monomer–dimer equilibrium has never been fully characterized for any receptor with a 2D equilibrium constant as well as association/dissociation rate constants (termed super-quantification). Here, we determined the dynamic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kasai, Rinshi S., Suzuki, Kenichi G. N., Prossnitz, Eric R., Koyama-Honda, Ikuko, Nakada, Chieko, Fujiwara, Takahiro K., Kusumi, Akihiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101103/
https://www.ncbi.nlm.nih.gov/pubmed/21300851
http://dx.doi.org/10.1083/jcb.201009128