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Single cell analysis applied to antibody fragment production with Bacillus megaterium: development of advanced physiology and bioprocess state estimation tools
BACKGROUND: Single cell analysis for bioprocess monitoring is an important tool to gain deeper insights into particular cell behavior and population dynamics of production processes and can be very useful for discrimination of the real bottleneck between product biosynthesis and secretion, respectiv...
Autores principales: | David, Florian, Berger, Antje, Hänsch, Robert, Rohde, Manfred, Franco-Lara, Ezequiel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101136/ https://www.ncbi.nlm.nih.gov/pubmed/21496219 http://dx.doi.org/10.1186/1475-2859-10-23 |
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