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TF-Cluster: A pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM)

BACKGROUND: Identifying the key transcription factors (TFs) controlling a biological process is the first step toward a better understanding of underpinning regulatory mechanisms. However, due to the involvement of a large number of genes and complex interactions in gene regulatory networks, identif...

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Detalles Bibliográficos
Autores principales: Nie, Jeff, Stewart, Ron, Zhang, Hang, Thomson, James A, Ruan, Fang, Cui, Xiaoqi, Wei, Hairong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101171/
https://www.ncbi.nlm.nih.gov/pubmed/21496241
http://dx.doi.org/10.1186/1752-0509-5-53