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TF-Cluster: A pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM)
BACKGROUND: Identifying the key transcription factors (TFs) controlling a biological process is the first step toward a better understanding of underpinning regulatory mechanisms. However, due to the involvement of a large number of genes and complex interactions in gene regulatory networks, identif...
Autores principales: | Nie, Jeff, Stewart, Ron, Zhang, Hang, Thomson, James A, Ruan, Fang, Cui, Xiaoqi, Wei, Hairong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101171/ https://www.ncbi.nlm.nih.gov/pubmed/21496241 http://dx.doi.org/10.1186/1752-0509-5-53 |
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