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RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation

T cell fate is associated with mutually exclusive expression of CD4 or CD8 in helper and cytotoxic T cells, respectively. How expression of one locus is temporally coordinated with repression of the other has been a long-standing enigma, though we know RUNX transcription factors activate the Cd8 loc...

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Detalles Bibliográficos
Autores principales:	Collins, Amélie, Hewitt, Susannah L., Chaumeil, Julie, Sellars, MacLean, Micsinai, Mariann, Allinne, Jeanne, Parisi, Fabio, Nora, Elphège P., Bolland, Dan J., Corcoran, Anne E., Kluger, Yuval, Bosselut, Remy, Ellmeier, Wilfried, Chong, Mark M.W., Littman, Dan R., Skok, Jane A.
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101577/ https://www.ncbi.nlm.nih.gov/pubmed/21435585 http://dx.doi.org/10.1016/j.immuni.2011.03.004

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