Cargando…

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion

Phosphoinositide 3-kinase (PI3K) p110 isoforms are membrane lipid kinases classically involved in signal transduction. Lipopolysaccharide (LPS)-activated macrophages constitutively and abundantly secrete proinflammatory cytokines including tumor necrosis factor-α (TNF). Loss of function of the p110δ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Low, Pei Ching, Misaki, Ryo, Schroder, Kate, Stanley, Amanda C., Sweet, Matthew J., Teasdale, Rohan D., Vanhaesebroeck, Bart, Meunier, Frédéric A., Taguchi, Tomohiko, Stow, Jennifer L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101599/ https://www.ncbi.nlm.nih.gov/pubmed/20837769 http://dx.doi.org/10.1083/jcb.201001028

Ejemplares similares

Phosphoinositide lipids in primary cilia biology
por: Conduit, Sarah E., et al.
Publicado: (2020)

NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells
por: Han, Haote, et al.
Publicado: (2023)

Targeting of proteins to the Golgi apparatus
por: Gleeson, Paul A., et al.
Publicado: (1994)

Regulation of a Golgi Flippase by Phosphoinositides and an ArfGEF
por: Natarajan, Paramasivam, et al.
Publicado: (2009)

Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase δ
por: Pagliuso, Alessandro, et al.
Publicado: (2016)

Phosphoinositide-mediated clathrin adaptor progression at the trans Golgi network
por: Daboussi, Lydia, et al.
Publicado: (2012)

Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation
por: Egami, Youhei, et al.
Publicado: (2014)

STING Operation at the ER/Golgi Interface
por: Taguchi, Tomohiko, et al.
Publicado: (2021)

The p110δ of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation
por: Guo, Hailong, et al.
Publicado: (2008)

Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry
por: Maccari, Maria Elena, et al.
Publicado: (2018)

Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K
por: Okkenhaug, Klaus, et al.
Publicado: (2007)

Sequential targeting of PI3Kδ and LAG3 as an effective anti-cancer approach
por: Lauder, Sarah N., et al.
Publicado: (2021)

Morphogenesis of post-Golgi transport carriers
por: Luini, Alberto, et al.
Publicado: (2008)

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
por: Coulter, Tanya I., et al.
Publicado: (2017)

Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network
por: Ito, Yoko, et al.
Publicado: (2021)

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ
por: Somoza, John R., et al.
Publicado: (2015)

Deconvolution of bulk RNA sequencing in activated phosphoinositide 3‐kinase δ syndrome
por: Huang, Xia, et al.
Publicado: (2023)

Activation of STING requires palmitoylation at the Golgi
por: Mukai, Kojiro, et al.
Publicado: (2016)

The Phosphoinositide 3-Kinase Isoform PI3Kβ Regulates Osteoclast-Mediated Bone Resorption in Humans and Mice
por: Győri, Dávid, et al.
Publicado: (2014)

Sac1–Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus
por: Cai, Yiying, et al.
Publicado: (2014)

Occurrence of B-cell lymphomas in patients with Activated Phosphoinositide 3-Kinase δ syndrome
por: Kracker, Sven, et al.
Publicado: (2014)

Distinct roles for phosphoinositide 3-kinases γ and δ in malignant B cell migration
por: Ali, Ahmed Y., et al.
Publicado: (2018)

ER-to-Golgi trafficking of procollagen in the absence of large carriers
por: McCaughey, Janine, et al.
Publicado: (2019)

Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase
por: Wood, Christopher S., et al.
Publicado: (2012)

PAQR3 Modulates Insulin Signaling by Shunting Phosphoinositide 3-Kinase p110α to the Golgi Apparatus
por: Wang, Xiao, et al.
Publicado: (2013)

SMAP2 Regulates Retrograde Transport from Recycling Endosomes to the Golgi
por: Matsudaira, Tatsuyuki, et al.
Publicado: (2013)

Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and inducible PIK3CD promoter
por: Whitehead, Maria A., et al.
Publicado: (2012)

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis
por: Greer, Yoshimi Endo, et al.
Publicado: (2014)

Case Report: First Occurrence of Plasmablastic Lymphoma in Activated Phosphoinositide 3-Kinase δ Syndrome
por: Yin, Zexi, et al.
Publicado: (2021)

Regulation of p110δ PI 3-Kinase Gene Expression
por: Kok, Klaartje, et al.
Publicado: (2009)

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities
por: Chandra, Mintu, et al.
Publicado: (2019)

Maturation of late Golgi cisternae into RabE(RAB11) exocytic post-Golgi carriers visualized in vivo
por: Pantazopoulou, Areti, et al.
Publicado: (2014)

Deficiency of p110δ Isoform of the Phosphoinositide 3 Kinase Leads to Enhanced Resistance to Leishmania donovani
por: Khadem, Forough, et al.
Publicado: (2014)

Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8(+) T Cell Survival, Differentiation, and Function
por: Cannons, Jennifer L., et al.
Publicado: (2018)

Airway epithelial phosphoinositide 3-kinase-δ contributes to the modulation of fungi-induced innate immune response
por: Jeong, Jae Seok, et al.
Publicado: (2018)

Cryptotanshinone Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide-3-Kinase-δ in Chronic Obstructive Pulmonary Disease
por: Xie, Tao, et al.
Publicado: (2023)

Two cases of successful sirolimus treatment for patients with activated phosphoinositide 3-kinase δ syndrome 1
por: Jiang, Lu, et al.
Publicado: (2023)

Phosphoinositide-Dependent Protein Kinases Regulate Cell Cycle Progression Through the SAD Kinase Cdr2 in Fission Yeast
por: Liu, Kun, et al.
Publicado: (2022)

Protein Kinase A Activity Is Necessary for Fission and Fusion of Golgi to Endoplasmic Reticulum Retrograde Tubules
por: Tenorio, María J., et al.
Publicado: (2015)

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions
por: Miserey-Lenkei, Stéphanie, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_loom35lqpnrviu6tu9bea4fqve