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Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease

Recent studies show that in Alzheimer's disease (AD), alterations in neurogenesis contribute to the neurodegenerative process. Neurodegeneration in AD has been associated with aberrant signaling through the cyclin-dependent kinase-5 (CDK5) pathway via its activators p35/p25; however, the role o...

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Detalles Bibliográficos
Autores principales:	Crews, L, Patrick, C, Adame, A, Rockenstein, E, Masliah, E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101702/ https://www.ncbi.nlm.nih.gov/pubmed/21368891 http://dx.doi.org/10.1038/cddis.2011.2

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