Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract

The mucosal epithelium is the initial target for respiratory pathogens of all types. While type I interferon (IFN) signaling is traditionally associated with antiviral immunity, we demonstrate that the extracellular bacterial pathogen Streptococcus pneumoniae activates the type I IFN cascade in airw...

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Detalles Bibliográficos
Autores principales: Parker, Dane, Martin, Francis J., Soong, Grace, Harfenist, Bryan S., Aguilar, Jorge L., Ratner, Adam J., Fitzgerald, Katherine A., Schindler, Christian, Prince, Alice
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101776/
https://www.ncbi.nlm.nih.gov/pubmed/21586648
http://dx.doi.org/10.1128/mBio.00016-11

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