HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1 release at the cell surface that can be overcome by the viral protein Vpu. Expression of Vpu results in a reduction of CD317 surface levels; however, the mechanism of this Vpu activity and its contribution to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Sarah, Fritz, Joëlle V., Bitzegeio, Julia, Fackler, Oliver T., Keppler, Oliver T.
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101777/
https://www.ncbi.nlm.nih.gov/pubmed/21610122
http://dx.doi.org/10.1128/mBio.00036-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101777/
https://www.ncbi.nlm.nih.gov/pubmed/21610122
http://dx.doi.org/10.1128/mBio.00036-11

Ejemplares similares