Cargando…

ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival

BACKGROUND: The clinico-pathological and molecular heterogeneity of epithelial ovarian cancer (EOC) complicates its early diagnosis and successful treatment. Highly aneuploid tumours and the presence of ascitic fluids are hallmarks of EOC. Two microcephaly-associated proteins, abnormal spindle-like...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brüning-Richardson, A, Bond, J, Alsiary, R, Richardson, J, Cairns, D A, McCormack, L, Hutson, R, Burns, P, Wilkinson, N, Hall, G D, Morrison, E E, Bell, S M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101901/ https://www.ncbi.nlm.nih.gov/pubmed/21505456 http://dx.doi.org/10.1038/bjc.2011.117

Ejemplares similares

Deregulation of Microcephalin and ASPM Expression Are Correlated with Epithelial Ovarian Cancer Progression
por: Alsiary, Rawiah, et al.
Publicado: (2014)

NuMA Overexpression in Epithelial Ovarian Cancer
por: Brüning-Richardson, Anke, et al.
Publicado: (2012)

No evidence that polymorphisms of brain regulator genes Microcephalin and ASPM are associated with general mental ability, head circumference or altruism
por: Rushton, J. Philippe, et al.
Publicado: (2007)

Tone and genes: New cross-linguistic data and methods support the weak negative effect of the “derived” allele of ASPM on tone, but not of Microcephalin
por: Dediu, Dan
Publicado: (2021)

Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment
por: Slade, M J, et al.
Publicado: (2009)

Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer
por: Morrison, D H, et al.
Publicado: (2012)

Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers
por: Shao, R, et al.
Publicado: (2011)

Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas
por: Bignotti, E, et al.
Publicado: (2008)

Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity
por: Wilson, G R, et al.
Publicado: (2006)

Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status
por: Fritzsche, F, et al.
Publicado: (2006)

Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma
por: Vasudev, N S, et al.
Publicado: (2009)

Association of serum amyloid A protein and peptide fragments with prognosis in renal cancer
por: Wood, S L, et al.
Publicado: (2010)

Fetal haemopoiesis marking low-grade urinary bladder cancer
por: Wolk, M, et al.
Publicado: (2012)

Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms
por: Nishikawa, G, et al.
Publicado: (2013)

Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas
por: Kitada, S, et al.
Publicado: (2013)

The Microcephalin Ancestral Allele in a Neanderthal Individual
por: Lari, Martina, et al.
Publicado: (2010)

Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer
por: Eisenach, P A, et al.
Publicado: (2013)

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells
por: Dixon, K M, et al.
Publicado: (2013)

Expression of lysophosphatidic acid acyltransferase beta (LPAAT-β) in ovarian carcinoma: correlation with tumour grading and prognosis
por: Niesporek, S, et al.
Publicado: (2005)

Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma
por: Baldan, V, et al.
Publicado: (2015)

PROX1 is a predictor of survival for gliomas WHO grade II
por: Elsir, T, et al.
Publicado: (2011)

Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy
por: Dunn, J M, et al.
Publicado: (2010)

A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial
por: Pinder, S E, et al.
Publicado: (2010)

Mcm2 predicts recurrence hazard in stage Ta/T1 bladder cancer more accurately than CK20, Ki67 and histological grade
por: Burger, M, et al.
Publicado: (2007)

Testicular microlithiasis as a familial risk factor for testicular germ cell tumour
por: Coffey, J, et al.
Publicado: (2007)

T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia
por: Steele, J C, et al.
Publicado: (2005)

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer
por: Rao, S R, et al.
Publicado: (2017)

An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study
por: Proctor, M J, et al.
Publicado: (2011)

Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways
por: Cleton-Jansen, A-M, et al.
Publicado: (2009)

PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness
por: Molleví, D G, et al.
Publicado: (2008)

Prognostic utility of HOXB13 : IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial
por: Jerevall, P-L, et al.
Publicado: (2011)

Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples
por: Hall, J S, et al.
Publicado: (2011)

Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer
por: Shaw, R J, et al.
Publicado: (2009)

Cisplatin plus paclitaxel and maintenance of bevacizumab on tumour progression, dissemination, and survival of ovarian carcinoma xenograft models
por: Oliva, P, et al.
Publicado: (2012)

An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes
por: Pinato, D J, et al.
Publicado: (2014)

Activation of the EGFR/ERK pathway in high-grade mucoepidermoid carcinomas of the salivary glands
por: Lujan, B, et al.
Publicado: (2010)

Similar protein expression profiles of ovarian and endometrial high-grade serous carcinomas
por: Hiramatsu, Kosuke, et al.
Publicado: (2016)

VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo
por: Rennel, E S, et al.
Publicado: (2009)

Androgen-related expression of G-proteins in ovarian cancer
por: Sheach, L A, et al.
Publicado: (2009)

Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive
por: O'Toole, A, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_g1to1ofa1c9l3lhoh9ut9euo8d