Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel

BACKGROUND: The development of androgen independence, chemo-, and radioresistance are critical markers of prostate cancer progression and the predominant reasons for its high mortality. Understanding the resistance to therapy could aid the development of more effective treatments. AIM: The aim of th...

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Detalles Bibliográficos
Autores principales: Uzoh, C C, Holly, J M P, Biernacka, K M, Persad, R A, Bahl, A, Gillatt, D, Perks, C M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101905/
https://www.ncbi.nlm.nih.gov/pubmed/21487405
http://dx.doi.org/10.1038/bjc.2011.127

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