Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration

BACKGROUND: Inflammatory breast cancer (IBC) is an aggressive subtype of breast cancer with distinct molecular profiles. Gene expression profiling previously identified sonic hedgehog (SHH) as part of a gene signature that is differentially regulated in IBC patients. METHODS: The effects of reducing...

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Detalles Bibliográficos
Autores principales: Thomas, Z I, Gibson, W, Sexton, J Z, Aird, K M, Ingram, S M, Aldrich, A, Lyerly, H K, Devi, G R, Williams, K P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101910/
https://www.ncbi.nlm.nih.gov/pubmed/21505458
http://dx.doi.org/10.1038/bjc.2011.133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101910/
https://www.ncbi.nlm.nih.gov/pubmed/21505458
http://dx.doi.org/10.1038/bjc.2011.133

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