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Comparison of HER2 status in primary and paired metastatic sites of gastric carcinoma
BACKGROUND: Trastuzumab has recently shown efficacy in the treatment of HER2-positive advanced gastric adenocarcinoma. Although antibody-based therapies target the metastatic disease, HER2 status is usually evaluated in the primary tumour because metastatic sites are rarely biopsied. The aim of this...
Autores principales: | Bozzetti, C, Negri, F V, Lagrasta, C A, Crafa, P, Bassano, C, Tamagnini, I, Gardini, G, Nizzoli, R, Leonardi, F, Gasparro, D, Camisa, R, Capelli, S, Silini, E M, Ardizzoni, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101935/ https://www.ncbi.nlm.nih.gov/pubmed/21487407 http://dx.doi.org/10.1038/bjc.2011.121 |
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