Cargando…
Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors
PURPOSE: Oxidative stress is implicit in the pathological changes associated with glaucoma. The purpose of this study was to compare levels of oxidative stress in glial fibrillary acid-negative protein (GFAP) lamina cribrosa (LC) cells obtained from the optic nerve head (ONH) region of 5 normal (NLC...
Autores principales: | McElnea, E.M., Quill, B., Docherty, N.G., Irnaten, M., Siah, W.F., Clark, A.F., O’Brien, C.J., Wallace, D.M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102025/ https://www.ncbi.nlm.nih.gov/pubmed/21617752 |
Ejemplares similares
-
Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells
por: McElnea, Elizabeth M, et al.
Publicado: (2014) -
Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts
por: Irnaten, Mustapha, et al.
Publicado: (2023) -
Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma
por: Murphy, Rory, et al.
Publicado: (2022) -
Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells
por: Kamel, Khalid, et al.
Publicado: (2020) -
Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma
por: Irnaten, Mustapha, et al.
Publicado: (2020)