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The Hexameric Structures of Human Heat Shock Protein 90
BACKGROUND: The human 90-kDa heat shock protein (HSP90) functions as a dimeric molecular chaperone. HSP90 identified on the cell surface has been found to play a crucial role in cancer invasion and metastasis, and has become a validated anti-cancer target for drug development. It has been shown to s...
Autores principales: | Lee, Cheng-Chung, Lin, Ta-Wei, Ko, Tzu-Ping, Wang, Andrew H.-J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102065/ https://www.ncbi.nlm.nih.gov/pubmed/21647436 http://dx.doi.org/10.1371/journal.pone.0019961 |
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