Cargando…

Tyrosine Sulfation of Native Mouse Psgl-1 Is Required for Optimal Leukocyte Rolling on P-Selectin In Vivo

BACKGROUND: We recently demonstrated that tyrosine sulfation is an important contributor to monocyte recruitment and retention in a mouse model of atherosclerosis. P-selectin glycoprotein ligand-1 (Psgl-1) is tyrosine-sulfated in mouse monocyte/macrophages and its interaction with P-selectin is impo...

Descripción completa

Detalles Bibliográficos
Autores principales: Westmuckett, Andrew D., Thacker, Kelly M., Moore, Kevin L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102115/
https://www.ncbi.nlm.nih.gov/pubmed/21633705
http://dx.doi.org/10.1371/journal.pone.0020406